PHA (Polyhydroxy Acids)
Gluconolactone, Lactobionic Acid, Maltobionic Acid
What is PHA (Polyhydroxy Acids)?
PHAs (Polyhydroxy Acids) are like the gentle cousins in the acid exfoliant family. These next-generation exfoliantsâincluding gluconolactone, lactobionic acid, and maltobionic acidâoffer many of the same benefits as AHAs (like glycolic acid) but with significantly less irritation potential.
Think of PHAs as the careful, patient exfoliators with a gentler touch. Their larger molecular structure means they cannot penetrate as deeply or quickly as other acidsâimagine them as having large, rounded edges that don't cut into the skin as sharply. This translates to effective exfoliation of dead skin cells at the surface level without disrupting the deeper, more sensitive layers of your skin.
What makes PHAs special is their multifunctional nature. Beyond exfoliation, they're powerful humectants that attract and hold moisture, and they also have antioxidant properties that help protect skin from environmental damage. It's like having an exfoliator that also functions as a moisturizer and protective shield.
For those with sensitive skin, rosacea, eczema, or those who've found other chemical exfoliants too harsh, PHAs provide that perfect middle groundâeffective renewal without the redness, irritation, or sensitivity that often accompanies stronger acids.
Perfect For
All skin types, particularly excellent for sensitive skin and acid beginners
Key Benefits
Core Competencies
Considerations & Cautions
Exceptionally gentle with very low irritation potential. Significantly less photosensitizing than AHAs. Suitable for conditions like rosacea and eczema where other acids may be too harsh.
Ingredient Interactions
Compatible with most skincare ingredients
Works well with: hydrating ingredients, barrier support ingredients
Can be used alongside: retinoids, vitamin C (with less risk of irritation than other acids)
Avoid: high pH products that would neutralize the acid
References
Journal of Cosmetic Dermatology, International Journal of Cosmetic Science