Oligopeptides

What is Oligopeptides?

Oligopeptides are the diverse special operations team of the peptide world—short chains of amino acids (typically 2-20) designed for specific missions within the skin. These versatile compounds come in numerous variations, each engineered to target particular skin concerns from pigmentation to firmness. Think of them as customized task forces assembled for specific objectives rather than general improvement. It's the skincare equivalent of precision medicine—targeted interventions designed for specific outcomes rather than one-size-fits-all approaches. For those with clearly defined skin concerns seeking focused improvement rather than general anti-aging benefits, specific oligopeptides (such as oligopeptide-34 for brightening or oligopeptide-24 for repair) offer tailored solutions with concentrated efficacy, though they work best when integrated into comprehensive formulations that address multiple aspects of skin health simultaneously rather than as standalone hero ingredients.

Perfect For

Oily: Neutral effect on oily skin
Dry: Neutral effect on dry skin
Sensitive: Neutral effect on sensitive skin
Combination: Depends on specific formulation and application technique
Mature: Highly beneficial - addresses multiple signs of aging

Key Benefits

anti-aging collagen support

Core Competencies

fine lines wrinkles loss of firmness elasticity loss sagging

Ingredient Interactions

Works well with: hyaluronic acid, niacinamide, antioxidants

Avoid combining with: aha, bha, direct acids, copper peptides with vitamin c

Notes: Works well in hydrating, repairing formulas; some peptides are pH sensitive

References

Strength: Moderate - Some clinical evidence

Key Studies:
• Lupo MP, et al. Journal of Drugs in Dermatology (2007): Study on peptides in dermatology
• Schagen SK. Cosmetics (2017): Review of topical peptides for skin aging
• Robinson LR, et al. International Journal of Cosmetic Science (2005): Research on specific peptides

Mechanisms:
• Signal peptides stimulate collagen, elastin, and other proteins
• Carrier peptides deliver trace elements necessary for wound healing
• Neurotransmitter inhibitor peptides reduce muscle contractions
• Enzyme inhibitor peptides block processes that break down collagen