Niacinamide
What is Niacinamide?
Niacinamide is a active ingredient that provides targeted treatment benefits through biochemical interactions. It provides anti-aging, brightening and melanin transfer inhibition benefits. It's particularly beneficial for addressing fine lines, wrinkles and loss of firmness. among other skin concerns. Results are typically seen in the immediate (hours to days). It is most effective at a concentration of 2-10%. It's a versatile ingredient that's well-tolerated by most skin types.
Perfect For
Oily: Highly beneficial - helps regulate sebum production and reduces breakouts
Dry: Neutral effect on dry skin
Sensitive: Generally beneficial - helps strengthen skin barrier
Combination: Highly beneficial - balances different zones of the face
Mature: Highly beneficial - addresses multiple signs of aging
Key Benefits
Core Competencies
Considerations & Cautions
Generally well-tolerated even at higher concentrations. May cause flushing in some individuals when used at high concentrations or with acidic products.
Ingredient Interactions
Works well with: hyaluronic acid, retinol, peptides, ceramides, zinc
Avoid combining with: vitamin c, ascorbic acid
Notes: Versatile ingredient that pairs well with most other actives; may cause flushing with pure L-ascorbic acid
References
Strength: Strong - Multiple clinical trials
Key Studies:
• Bissett D, et al. Dermatologic Surgery (2005): Showed reduction in hyperpigmentation and redness
• Matts P, et al. Journal of Cosmetic Dermatology (2002): Demonstrated barrier function improvement
• Navarrete-Solís J, et al. Dermatology Research and Practice (2011): Compared efficacy to hydroquinone
Mechanisms:
• Improves barrier function by increasing ceramide production
• Reduces melanin transfer to keratinocytes
• Anti-inflammatory effects reduce redness
• Regulates sebum production